Anaplastic Kaposi's sarcoma: an uncommon histologic phenotype with an aggressive clinical course
Identifieur interne : 005E04 ( Main/Exploration ); précédent : 005E03; suivant : 005E05Anaplastic Kaposi's sarcoma: an uncommon histologic phenotype with an aggressive clinical course
Auteurs : Yue Yu [États-Unis] ; Marie-France Demierre [États-Unis] ; Meera Mahalingam [États-Unis]Source :
- Journal of Cutaneous Pathology [ 0303-6987 ] ; 2010-10.
Abstract
Anaplastic Kaposi sarcoma (KS) is an uncommon histologic phenotype of Kaposi's and one that is typically associated with a locally aggressive clinical course. We report a case of a 53‐year‐old human immunodeficiency virus‐positive male, on highly active antiretroviral therapy 1 month prior to admission, who presented with fever, cough, respiratory distress, multiple skin lesions and cervical and inguinal lymphadenopathy not responding to multiple antibiotics. Microscopic examination of punch biopsies from the forehead and chest revealed a spindled cell neoplasm with marked cytologic atypia and scattered mitoses, features consistent with a diagnosis of anaplastic KS and confirmed by immunohistochemistry with HHV‐8. Biopsy of an involved lymph node also revealed involvement by KS. Despite aggressive clinical treatment, the patient rapidly deteriorated and expired 1 week after the diagnosis of anaplastic KS was rendered. Our case underscores the aggressive clinical course of this uncommon histologic variant of KS and its recalcitrant clinical behavior. Yu Y, Demierre M‐F, Mahalingam M. Anaplastic Kaposi's sarcoma: an uncommon histologic phenotype with an aggressive clinical course.
Url:
DOI: 10.1111/j.1600-0560.2009.01389.x
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 004198
- to stream Istex, to step Curation: 004198
- to stream Istex, to step Checkpoint: 000B48
- to stream Main, to step Merge: 005E59
- to stream Main, to step Curation: 005E04
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Anaplastic Kaposi's sarcoma: an uncommon histologic phenotype with an aggressive clinical course</title><author><name sortKey="Yu, Yue" sort="Yu, Yue" uniqKey="Yu Y" first="Yue" last="Yu">Yue Yu</name></author><author><name sortKey="Demierre, Marie Rance" sort="Demierre, Marie Rance" uniqKey="Demierre M" first="Marie-France" last="Demierre">Marie-France Demierre</name></author><author><name sortKey="Mahalingam, Meera" sort="Mahalingam, Meera" uniqKey="Mahalingam M" first="Meera" last="Mahalingam">Meera Mahalingam</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:8C0E7E6AB1C1F07F7C81DFDC194A33A4A3ABA08B</idno><date when="2010" year="2010">2010</date><idno type="doi">10.1111/j.1600-0560.2009.01389.x</idno><idno type="url">https://api.istex.fr/document/8C0E7E6AB1C1F07F7C81DFDC194A33A4A3ABA08B/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">004198</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">004198</idno><idno type="wicri:Area/Istex/Curation">004198</idno><idno type="wicri:Area/Istex/Checkpoint">000B48</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000B48</idno><idno type="wicri:doubleKey">0303-6987:2010:Yu Y:anaplastic:kaposi:s</idno><idno type="wicri:Area/Main/Merge">005E59</idno><idno type="wicri:Area/Main/Curation">005E04</idno><idno type="wicri:Area/Main/Exploration">005E04</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Anaplastic Kaposi's sarcoma: an uncommon histologic phenotype with an aggressive clinical course</title><author><name sortKey="Yu, Yue" sort="Yu, Yue" uniqKey="Yu Y" first="Yue" last="Yu">Yue Yu</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Dermatology, Boston University School of Medicine, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Tufts University School of Medicine, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Demierre, Marie Rance" sort="Demierre, Marie Rance" uniqKey="Demierre M" first="Marie-France" last="Demierre">Marie-France Demierre</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Dermatology, Boston University School of Medicine, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Mahalingam, Meera" sort="Mahalingam, Meera" uniqKey="Mahalingam M" first="Meera" last="Mahalingam">Meera Mahalingam</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Dermatopathology Section, Department of Dermatology, Boston University School of Medicine, Boston, MA</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="1"><country wicri:rule="url">États-Unis</country></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Journal of Cutaneous Pathology</title><title level="j" type="alt">JOURNAL OF CUTANEOUS PATHOLOGY</title><idno type="ISSN">0303-6987</idno><idno type="eISSN">1600-0560</idno><imprint><biblScope unit="vol">37</biblScope><biblScope unit="issue">10</biblScope><biblScope unit="page" from="1088">1088</biblScope><biblScope unit="page" to="1091">1091</biblScope><biblScope unit="page-count">4</biblScope><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2010-10">2010-10</date></imprint><idno type="ISSN">0303-6987</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0303-6987</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Anaplastic Kaposi sarcoma (KS) is an uncommon histologic phenotype of Kaposi's and one that is typically associated with a locally aggressive clinical course. We report a case of a 53‐year‐old human immunodeficiency virus‐positive male, on highly active antiretroviral therapy 1 month prior to admission, who presented with fever, cough, respiratory distress, multiple skin lesions and cervical and inguinal lymphadenopathy not responding to multiple antibiotics. Microscopic examination of punch biopsies from the forehead and chest revealed a spindled cell neoplasm with marked cytologic atypia and scattered mitoses, features consistent with a diagnosis of anaplastic KS and confirmed by immunohistochemistry with HHV‐8. Biopsy of an involved lymph node also revealed involvement by KS. Despite aggressive clinical treatment, the patient rapidly deteriorated and expired 1 week after the diagnosis of anaplastic KS was rendered. Our case underscores the aggressive clinical course of this uncommon histologic variant of KS and its recalcitrant clinical behavior. Yu Y, Demierre M‐F, Mahalingam M. Anaplastic Kaposi's sarcoma: an uncommon histologic phenotype with an aggressive clinical course.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Massachusetts</li></region></list><tree><country name="États-Unis"><region name="Massachusetts"><name sortKey="Yu, Yue" sort="Yu, Yue" uniqKey="Yu Y" first="Yue" last="Yu">Yue Yu</name></region><name sortKey="Demierre, Marie Rance" sort="Demierre, Marie Rance" uniqKey="Demierre M" first="Marie-France" last="Demierre">Marie-France Demierre</name><name sortKey="Mahalingam, Meera" sort="Mahalingam, Meera" uniqKey="Mahalingam M" first="Meera" last="Mahalingam">Meera Mahalingam</name><name sortKey="Mahalingam, Meera" sort="Mahalingam, Meera" uniqKey="Mahalingam M" first="Meera" last="Mahalingam">Meera Mahalingam</name><name sortKey="Yu, Yue" sort="Yu, Yue" uniqKey="Yu Y" first="Yue" last="Yu">Yue Yu</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 005E04 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 005E04 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:8C0E7E6AB1C1F07F7C81DFDC194A33A4A3ABA08B
|texte= Anaplastic Kaposi's sarcoma: an uncommon histologic phenotype with an aggressive clinical course
}}
| This area was generated with Dilib version V0.6.31. |  |